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The 2-Desamino and 2-Desamino-2-methyl Analogues of Aminopterin Do Not Inhibit Dihydrofolate Reductase but Are Potently Toxic to Tumor Cells in Culture

DOI: 10.1021/jm00123a001

Source and publish data:

Journal of Medicinal Chemistry p. 517 - 520 (1989)

Update date:2022-07-30

Topics:

Authors:

Rosowsky, Andre

Forsch, Ronald A.

Freisheim, James H.

Moran, Richard G.

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Article abstract of DOI:10.1021/jm00123a001

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Full text of DOI:10.1021/jm00123a001

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Product name:di-tert-butyl N-<4-<<(2-amino-3-cyanopyrazin-5-yl)methyl>amino>benzoyl>-L-glutamate

Cas No:118869-53-7

118869-53-7

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