A FORMAL TOTAL SYNTHESIS OF ERYTHROMYCIN A. 1. FACILE AND STEREOSELECTIVE SYNTHESES OF ERYTHRONOLIDE A SEGMENTS BASED ON ACYCLIC STEREOCONTROL

DOI: 10.1016/S0040-4039(00)86716-7

Source and publish data:

Tetrahedron Letters p. 2219 - 2222 (1988)

Update date:2022-08-04

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Authors:

Nakata, Tadashi

Fukui, Mineo

Oishi, Takeshi

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Article abstract of DOI:10.1016/S0040-4039(00)86716-7

Two segments, corresponding to the C1-C7 and C8-C15 parts of erythronolide A, were synthesized stereoselectively from the optically active syn-α-methyl-β-hydroxy imides prepared by Zn(BH4)2 reduction of the corresponding β-keto imides.

Full text of DOI:10.1016/S0040-4039(00)86716-7

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