Effect of Triphenylacrylonitrile Derivatives on Estradiol-Receptor Binding and on Human Breast Cancer Cell Growth

DOI: 10.1021/jm00129a013

Source and publish data:

Journal of Medicinal Chemistry p. 2092 - 2103 (1989)

Update date:2022-08-05

Topics: Molecular structure Derivatives Cell Culture Statistical Analysis Experimental Design Binding assay Control group Treatment group

Authors:

Bignon, Eric

Pons, Michel

Paulet, Andre Crastes de

Dore, Jean-Christophe

Gilbert, Jacques

et al. et al.

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Article abstract of DOI:10.1021/jm00129a013

In a study of a series of 26 triphenylacrylonitrile derivatives (TPEs), we investigated the influence of several possibly interrelated factors on the proliferation of human breast cancer cell lines. (1) Chemical substituents: the test compounds were for t

Full text of DOI:10.1021/jm00129a013

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