SYNTHESE EN UNE ETAPE D'α-ALCOXYHYDRAZIDES, DE DERIVES D'α-AMINOACIDES ET D'α-HYDROXYACIDES A PARTIR DES α-HALOGENOHYDRAZIDES. ETUDE DU MECANISME DE LA REACTION.

DOI: 10.1016/S0040-4020(01)86184-6

Source and publish data:

Tetrahedron p. 4805 - 4814 (1988)

Update date:2022-09-26

Topics:

Authors:

Legrel, P.

Baudy-Floc'h, M.

Robert, A.

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Article abstract of DOI:10.1016/S0040-4020(01)86184-6

α-Halohydrazides react with nucleophiles under basic conditions to give α-functionalized hydrazides.We have shown that this reaction is not a direct nucleophilic substitution of the halogen but more likely proceeds through the formation of an aziridinone

Full text of DOI:10.1016/S0040-4020(01)86184-6

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