
Tetrahedron p. 3231 - 3240 (1988)
Update date:2022-08-05
Topics: Enantiomer Acylation Microwave-assisted synthesis Column chromatography Yield NMR spectroscopy Catalyst HPLC Nucleophile Electrophile Chiral center Recrystallization Lactam TLC (thin-layer chromatography) Protecting group β-Lactam Ring-Opening Diastereomer Solvent extraction Reaction quenching
Tamura, Norikazu
Matsushita, Yoshihiro
Yoshioka, Kouichi
Ochiai, Michihiko
Aza analogues of lactivicin (1), a recently discovered novel antibiotic, were prepared by an application of our earlier convenient synthesis of 1 and its derivatives.A 1-unsubstituted pyrazolidinone derivative bearing 2-aminothiazol-4-yl-(Z)-methoxyiminoa
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