Unusual Addition and Cycloaddition Reactions of 2-Amino-3-cyanopyrroles with Dimethyl Acetylenedicarboxylate and Methyl Propynoate

DOI: 10.1055/s-1988-27661

Source and publish data:

Synthesis p. 632 - 635 (1988)

Update date:2022-09-26

Topics:

Authors:

Eger, Kurt

Folkers, Gerd

Frey, Martina

Zimmermann, Werner

Koop-Kirfel, Gabriele

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Article abstract of DOI:10.1055/s-1988-27661

Amino group activated 4,5-dimethylpyrroles react with acetylenecarboxylate derivatives in a hitherto unknown manner.The formation of the 5-indolone derivatives 6a, b, c, e, g, h as main products depends on the solvent medium.The 1:2 addition product 3a shows an unusual reactivity yielding the isoindole derivative 4a and the isoquinoline derivative 5a.

Full text of DOI:10.1055/s-1988-27661

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