Unusual Addition and Cycloaddition Reactions of 2-Amino-3-cyanopyrroles with Dimethyl Acetylenedicarboxylate and Methyl Propynoate

DOI: 10.1055/s-1988-27661

Source and publish data:

Synthesis p. 632 - 635 (1988)

Update date:2022-09-26

Topics:

Authors:

Eger, Kurt

Folkers, Gerd

Frey, Martina

Zimmermann, Werner

Koop-Kirfel, Gabriele

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1988-27661

Amino group activated 4,5-dimethylpyrroles react with acetylenecarboxylate derivatives in a hitherto unknown manner.The formation of the 5-indolone derivatives 6a, b, c, e, g, h as main products depends on the solvent medium.The 1:2 addition product 3a shows an unusual reactivity yielding the isoindole derivative 4a and the isoquinoline derivative 5a.

Full text of DOI:10.1055/s-1988-27661

Products guided by the article

Product name:2-Amino-5,7a-dihydro-7a-methyl-5-oxo-1-phenyl-1H-indol-3-carbonitril

Cas No:119215-44-0

R&D Labs maybe for 119215-44-0

Yurui(Shanghai)Chemical Co.,Ltd

Contact:0086 21-50456736

Address:No.3188 Xiupu Road,Shanghai
Xi'an Yuri Solar Co. Ltd

website:http://www.p-oled.cn/

Contact:+86-29-81101199

Address:No. 1199, Dingkunchi 3rd Road, High Tech Zone, Xi'an, Shaanxi, China,710119
Jiangsu Taihu New Materials Holding Co., Ltd

Contact:+86-519-86160108

Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China
Sinoway International (Jiangsu) Co., Ltd.

Contact:+86-25-86630167

Address:17 Beijing Road (West), Nanjing, China
Jinan Yijialian Economic and Trade Development Co., Ltd.

Contact:+86 0531-66729596

Address:jinan

Relevant to this article

Doi:10.1021/ja00368a059
(1982)
Unexpected behavior of the reaction between acyl thioformanilides and acetonitrile derivatives-a useful entry to new penta-substituted dipyrrole disulfides

Doi:10.1016/j.tetlet.2009.09.020
(2009)
Novel orally active morpholine N-arylsulfonamides γ-secretase inhibitors with low CYP 3A4 liability

Doi:10.1016/j.bmcl.2009.09.055
(2009)
Solid-phase synthesis of 4(5),1′,5′-trisubstituted 2,4′-biimidazoles

Doi:10.1021/jo902122e
(2009)
Total synthesis of (±)-N-(phenylsulfonyl)- and (±)-N-(tert-butyloxycarbonyl)-CI, (±)-CI-CDPI₁, and (±)-CI-CDPI₂: CC-1065 functional analogues incorporating the parent 1,2,7,7a-tetrahydrocycloprop[1,2-c]indol-4-one (CI) left-hand subu

Doi:10.1021/jo00267a004
(1989)
Synthesis of a Resorcylic Acid Lactone (RAL) library using fluorous-mixture synthesis and profile of its selectivity against a panel of kinases

Doi:10.1002/chem.200901375
(2009)

Article Doi