Recognition of CG interrupting site by W-shaped nucleoside analogs (WNA) having the pyrazole ring in an anti-parallel triplex DNA

DOI: 10.1016/j.bmc.2009.08.040

Source and publish data:

Bioorganic and Medicinal Chemistry p. 6803 - 6810 (2009)

Update date:2022-09-26

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Authors:

Taniguchi, Yosuke

Uchida, Yuko

Takaki, Tomoko

Aoki, Eriko

Sasaki, Shigeki

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Article abstract of DOI:10.1016/j.bmc.2009.08.040

We have previously developed W-shaped nucleoside analogs (WNA) for recognition of TA and CG interrupting sites, which are the intrinsic limitation for the formation of a stable triplex DNA by the natural triplex-forming oligonucleotide (TFO). However, the

Full text of DOI:10.1016/j.bmc.2009.08.040

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