Tetrahedron Letters p. 4513 - 4516 (1988)
Update date:2022-07-30
Topics:
Wehmeyer, Richard M.
Rieke, Reuben D
Highly reactive copper solutions have been prepared by the lithium naphtalide reduction of copper(I) iodide/triphenyl-phosphine complex.These copper solutions react rapidly with functionalized alkyl halides to give organocopper reagents wich have been effectively trapped with acid chlorides giving functionalized ketones in good yields.Ester, nitrile, chloride, remote epoxide, and, to some degree, ketone groups can be tolerated by this approach.
View MoreBeijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Shanghai Forever Synthesis Co.,Ltd.
Contact:021-61124658
Address:Zhoukang Road,Pudong New District,Shanghai,China
Contact:86-511-85210668 0511-85210668, 85210818, 85210898
Address:Yihai Garden E-902,NO.99 Daxi RD., Zhenjiang Jiiangsu ,China
Contact:+86-371-67759225
Address:No.32, Jinsuo Road, High-tech Zone
Zhengzhou Institute of Chiral Pharmer Research Co., Ltd.
Contact:86-371-55219111
Address:15 Floor, 2 Building, Central China Technovalley, Zhongyuan West Road
Doi:10.1021/jm9015075
(2010)Doi:10.1080/00397910903219369
(2010)Doi:10.1002/anie.200904766
(2009)Doi:10.1134/S107042800908017X
(2009)Doi:10.1016/j.tetlet.2009.10.136
(2010)Doi:10.1139/v71-188
(1971)
