Synthesis of 2,3-diaziridinyl-1,4-naphthoquinone sulfonate derivatives as potential antineoplastic agents

DOI: 10.1021/jm00127a012

Source and publish data:

Journal of Medicinal Chemistry p. 1467 - 1471 (1989)

Update date:2022-09-26

Topics:

Authors:

Lin Lin

Zhu Zhu

Cosby Cosby

Sartorelli

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Article abstract of DOI:10.1021/jm00127a012

A new class of 2,3-diaziridinyl-1,4-naphthoquinone sulfonates (27 compounds) has been synthesized and evaluated as potential antineoplastic agents. The most active compounds, benzenesulfonate 4, p-toluenesulfonate 5, p-methoxylbenzenesulfonate 7, 8-quinol

Full text of DOI:10.1021/jm00127a012

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Product name:1,4-Naphthalenedione, 2,3-bis(1-aziridinyl)-5-[[(4-methylphenyl)sulfonyl]oxy]-

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