A CYANIDE PROMOTED MICHAEL REACTION: THE USE OF AN AMINONITRILE AS AN ENAMINE EQUIVALENT FOR THE MICHAEL REACTION

DOI: 10.1016/S0040-4039(00)88452-X

Source and publish data:

Tetrahedron Letters p. 6831 - 6834 (1988)

Update date:2022-08-04

Topics:: Authors:

Mitch, Charles H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)88452-X

An enamine lacking a beta-proton is shown to undergo the Michael reaction if the intermediate iminium ion is trapped with a nucleophile, such as cyanide.Reductive cleavage of the resulting nitrile affords an aminoketone product.

Full text of DOI:10.1016/S0040-4039(00)88452-X

Products guided by the article

Product name:[1-Ethyl-4-(3-methoxy-phenyl)-4-methyl-1,4,5,6-tetrahydro-pyridin-3-ylmethyl]-dimethyl-amine

Cas No:120658-39-1

R&D Labs maybe for 120658-39-1

STAR SYNTHESIS CO.,LIMITED

Contact:+(852) 301-98033

Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong
WD Silicone Co., Ltd

Contact:+86-27-87204219, +86-27-87215023

Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Anhui Hope-Chem Co., Ltd.

Contact:86-551-63540590

Address:No 1388 Furong Rd., Hefei, Anhui, China
TIANJIN DONGRUXIANG MINERALS MARKETING CO.,LTD(expird)

Contact:22-58516360

Address:tianjin
New Forms

Contact:+31-24-3886056

Address:Binderskampweg 29 Unit 36

Relevant to this article

Thermal ring opening of 1,1-dibromo and 1-bromo-2- chloromethylcyclopropanes: Observation of a formal debromochlorination

Doi:10.1007/s00706-008-0076-4
(2009)
The dynamic assembly of covalent organic polygons: Finding the optimal balance of solubility, functionality, and stability

Doi:10.1002/ejoc.201500170
(2015)
Use of β,γ-unsaturated α-ketocarbonyls for a totally regioselective oxidative multicomponent synthesis of polyfunctionalized pyridines

Doi:10.1002/chem.200902491
(2009)
Carbamate Synthesis Using a Shelf-Stable and Renewable C₁ Reactant

Doi:10.1002/cssc.201900406
(2019)
Evaluation of secondary amide replacements in a series of CCR5 antagonists as a means to increase intrinsic membrane permeability. Part 1: Optimization of gem-disubstituted azacycles

Doi:10.1016/j.bmcl.2009.11.072
(2010)
Novel synthesis of amphiphilic dendrons by the double-stage convergent method

Doi:10.1021/ol901765f
(2009)

Article Doi

A CYANIDE PROMOTED MICHAEL REACTION: THE USE OF AN AMINONITRILE AS AN ENAMINE EQUIVALENT FOR THE MICHAEL REACTION

DOI: 10.1016/S0040-4039(00)88452-X

Source and publish data:

Authors:

Article abstract of DOI:10.1016/S0040-4039(00)88452-X

Full text of DOI:10.1016/S0040-4039(00)88452-X

Products guided by the article

R&D Labs maybe for 120658-39-1

Relevant to this article

Hot Product