Tetrahedron Letters p. 6831 - 6834 (1988)
Update date:2022-08-04
Topics:
Mitch, Charles H.
An enamine lacking a beta-proton is shown to undergo the Michael reaction if the intermediate iminium ion is trapped with a nucleophile, such as cyanide.Reductive cleavage of the resulting nitrile affords an aminoketone product.
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