Organic Letters
Letter
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alkynoates, during which two new C−C bonds were formed in
one step, toward the synthesis of the biologically attractive
coumarin core structure in moderate to good yields. This
procedure avoids limitations commonly associated with
transition-metal-mediated C−H activation, including require-
ments for high reaction temperatures and chelating directing
groups. Further applications of this protocol in organic
synthesis are currently underway in our laboratory.
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ASSOCIATED CONTENT
* Supporting Information
■
S
The Supporting Information is available free of charge on the
Detailed experimental procedures and full spectroscopic
data for all new compounds (PDF)
AUTHOR INFORMATION
Corresponding Author
■
Notes
The authors declare no competing financial interest.
(12) For metal-free reactions, see: (a) Mi, X.; Wang, C.; Huang, M.;
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51, 768. (c) Yang, W.; Yang, S.; Li, P.; Wang, L. Chem. Commun. 2015,
51, 7520.
ACKNOWLEDGMENTS
■
This work was supported by the National Science Foundation
of China (21472079 and 21572088), PCSIRT (IRT_15R28),
and the Fundamental Research Funds for the Central
Universities (lzujbky-2015-50, lzujbky-2016-ct02).
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