Tetrahedron p. 1979 - 1990 (1988)
Update date:2022-08-03
Topics:
Gosselin, Pascal
A new synthetic route to γ-Damascone 1 starting with methyl-γ-dithiocyclogeranate 2 is described.Addition of HMPT was found necessary to perform the carbophilic addition of allylmagnesium bromide on dithioester 2.A dienylsulfide, 6,6-dimethyl-2-methylene-(1-methylthio-1,3-butadiene)-1-yl cyclohexane 3 resulted from this addition, and not the expected dithioketal.Following a number of described conditions, hydrolysis of 3 to γ-damascone 1 proved to be unsatisfactory.These initial attempts but showed the necessity for an acidic medium.This finding allowed the development of a new, very mild method of hydrolysis of dienylsulfides to unsaturated ketones.
View MoreQINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.
Contact:+86 532 80861829
Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Shandong LuZhou Amino Acid Co., Ltd
Contact:86-539-2218025
Address:yishui economic and technical development zone zhenxing south road
Shanghai PengMo Biotechnology Co.,Ltd
website:http://www.pengmobio.lookchem.com
Contact:86-13052359378
Address:No.218 Hai Qu Road.Shanghai.China
website:http://www.sdowchem.com
Contact:86-135-2193 7483
Address:8-106 taiyue building
taicang liyuan chemical co,.ltd
website:http://www.tcliyuanchem.com/productse.php
Contact:86-512-53539583
Address:Room 804,Huaxu Building,No.95,Renmin South Road,Taicang city,Jiangsu Province,China
Doi:10.1246/bcsj.61.4347
(1988)Doi:10.1002/ardp.19893220108
(1989)Doi:10.1039/DT9910000949
(1991)Doi:10.1055/s-0034-1378805
(2015)Doi:10.1002/chem.201402524
(2015)Doi:10.1055/s-1988-27781
(1988)
