Transition Metal-Catalyzed, Chlorine-Transfer Radical Cyclizations of 2-(3-Alken-1-oxy)-2-chloroacetates. Formal Total Synthesis of Avenaciolide and Isoavenaciolide

DOI: 10.1021/jo00087a011

Source and publish data:

Journal of Organic Chemistry p. 1993 - 2003 (1994)

Update date:2022-08-04

Topics:

Authors:

Udding, Jan H.

Tuijp, Kees (C.) J. M.

Zanden, Marco N. A. van

Hiemstra, Henk

Speckamp, W. Nico

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00087a011

A novel method for the synthesis of functionalized tetrahydrofurans is described.This method involves the treatment of 2-(3-alken-1-oxy)-2-chloroacetates 1 with a catalytic amount of Cu(bpy)Cl in refluxing 1,2-dichloroethane to give good yields of 3-(1-ch

Full text of DOI:10.1021/jo00087a011

Products guided by the article

Product name:2-Carbomethoxy-4-chloro-5,6-dihydro-2H-pyran

Cas No:121223-20-9

R&D Labs maybe for 121223-20-9

Shanghai Puda Chemical Co.,Ltd

Contact:+86+571+56565965

Address:10F Haiyue Building,Danfeng Road,Binjiang District,Hangzhou,China
Chengdu D-Innovation Pharmaceutical Co., Ltd

Contact:86-28-85105536

Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
Chemsigma International Co.,Ltd.

website:http://www.chemsigma.com

Contact:86-025-58748998

Address:Rm.705, 15th Building,Rd.Xinke II
Shandong Jincheng Zhonghua Bio-pharmaceutical Co.,Ltd

Contact:+86-533-5415882

Address:Zichuan Economic Development Zone,Zibo City,Shandong Province,China
H&Y International Group Ltd

Contact:+86-571-86491666

Address:SHI XIANG ROAD

Relevant to this article

OSMYLATION OF HIGHER SUGAR ALLYLIC ALCOHOLS

Doi:10.1016/0008-6215(88)84075-8
(1988)
Doi:10.1055/s-1970-21635
(1970)
Total synthesis of hyacinthacines B₃, B₄, and B ₅ and purported hyacinthacine B₇, 7-epi-hyacinthacine B₇, and 7a-epi-hyacinthacine B₃ from a common precursor

Doi:10.1021/jo5005923
(2014)
Environment friendly organic synthesis using bismuth compounds. An efficient method for carbonyl-ene reactions catalyzed by bismuth triflate

Doi:10.1016/j.tetlet.2005.09.035
(2005)
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl) propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus

Doi:10.1021/jm2014887
(2012)
Doi:10.1021/ja01181a011
(1948)

Article Doi