Chemistry of Heterocyclic Compounds p. 1113 - 1119 (1988)
Update date:2022-08-02
Topics:
Zvonok, A. M.
Biba, V. I.
Stanishevskii, L. S.
3-Hydroxy-4-piperidinones and 2-(α-hydroxyalkyl)-3-pyrrolidinones were obtained by the reaction of acryloyloxiranes with methylamine.It is shown that the regiospecifity of the heterocyclization of the products of addition of methylamine to the double bond of the acryloyloxirane is determined by the substituents attached to the α- and β-carbon atoms of the epoxide ring.
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