
Synthesis p. 983 - 988 (1994)
Update date:2022-09-26
Topics:
Ahlbrecht
Schmitt
Metalation of the 2-position in indolines is feasible via the dithiocarbamate derivative using s-butyllithium. In a one-pot procedure, treatment with alkyl halides, carbonyl compounds, oxiranes and imines leads to the corresponding 2-substituted indoline derivatives.
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