Tetrahedron Letters p. 5493 - 5496 (1988)
Update date:2022-07-29
Topics:
Urban, Frank J.
A new synthesis of spiro-benzopyran amino acids is presented.The key reaction is the intramolecular amidoalkylation of methyl 2-benzamido-4-(4-fluorophenoxy)-2-methoxybutyrate to yield methyl 4-benzamido-2,3-dihydro-6-fluoro-4H-benzopyran-4-carboxylate.
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