Synthesis of Biologically Active Carbocyclic Analogues of N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP)

Article abstract of DOI:10.1021/jo00277a002

Two biologically active analogues of MDP containing pseudo-D-glucosamine have been synthesised using as key step the Ferrier rearrangement (carbohydrate <*> inosose).Several different procedures for carrying out this reaction have been compared.