
European Journal of Medicinal Chemistry p. 909 - 914 (2010)
Update date:2022-07-30
Topics:
Sahoo, Prasanta Kumar
Behera, Pritishova
The acetic acid derivatives of [1,2,4]triazino[4,3-a]benzimidazole (TBI) were synthesized and tested in vitro and in vivo as selective aldose reductase (ALR2) inhibitors. Compound PS11 showed highest inhibitory activity (IC50) 0.32 μM and was f
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