2-(Aminomethyl)chromans That Inhibit Iron-Dependent Lipid Peroxidation and Protect against Central Nervous System Trauma and Ischemia

DOI: 10.1021/jm00101a025

Source and publish data:

Journal of Medicinal Chemistry p. 4464 - 4472 (1992)

Update date:2022-08-05

Topics:

Authors:

Jacobsen, E. Jon

VanDoornik, Fred J.

Ayer, Donald E.

Belonga, Kenneth L.

Braughler, J. Mark

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00101a025

A series of 2-(aminomethyl)chromans was developed as potent inhibitors of iron-dependent lipid peroxidation.Compounds within this class are extremely effective at inhibiting lipid peroxidation with IC50's as low as 0.2 μM.Selected members were found to en

Full text of DOI:10.1021/jm00101a025

Products guided by the article

Product name:1-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)carbonyl]-4-(4-methoxyphenyl)piperazine

Cas No:122003-25-2

R&D Labs maybe for 122003-25-2

Guangzhou Swan Chemical Co., Ltd.

Contact:+86-20-31075659

Address:NO.301, Hong ba fang investment BLDG 1,Guan chong village,Shiqi town,Panyu district,Guangzhou
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China
AstaTech ( Chengdu) BioPharmaceutical Corp.

website:http://www.astabiochem.cn/

Contact:+86-15198215156-15198215156

Address:SICHUAN CHENGDU
Changzhou Ruiping Chemical Co., Ltd

website:http://www.wishchem.com

Contact:+86-519-82324280

Address:No.288-1 Huacheng Road, Jintan
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou

Relevant to this article

Synthesis and properties of bis(pyrazino[2′,3′:4,5]imidazole)-fused 1,2,5,6-tetrahydro-1,4,5,8,9,10-hexaazaanthracenes: a new fluorescent nitrogen-rich heterocycle

Doi:10.1016/j.tetlet.2010.01.015
(2010)
Doi:10.1016/S0040-4039(01)92782-0
(1977)
Synthesis, molecular structure and evaluation of new organometallic ruthenium anticancer agents

Doi:10.1039/b918902e
(2009)
Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1α inhibitors

Doi:10.1016/j.bmcl.2009.12.037
(2010)
Synthesis and properties of Z-1, 3-bis- (aryl)-4-bromo-2-buten-1-ones

Doi:10.1007/s10593-010-0405-5
(2009)
Carbonyl umpolung reactivity of enals: NHC-catalyzed synthesis of aldol products via epoxide ring opening

Doi:10.1055/s-0029-1218563
(2010)

Article Doi