Journal of Medicinal Chemistry p. 4464 - 4472 (1992)
Update date:2022-08-05
Topics:
Jacobsen, E. Jon
VanDoornik, Fred J.
Ayer, Donald E.
Belonga, Kenneth L.
Braughler, J. Mark
et al.
A series of 2-(aminomethyl)chromans was developed as potent inhibitors of iron-dependent lipid peroxidation.Compounds within this class are extremely effective at inhibiting lipid peroxidation with IC50's as low as 0.2 μM.Selected members were found to en
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