A NOVEL OXIDATIVE RING-OPENING REACTION OF ISOXAZOLIDINES: SYNTHESES OF β-AMINO KETONES AND β-AMINO ACID ESTERS FROM SECONDARY AMINES

DOI: 10.1016/S0040-4039(00)82237-6

Source and publish data:

Tetrahedron Letters p. 5949 - 5952 (1988)

Update date:2022-08-05

Topics:

Authors:

Murahashi, Shun-Ichi

Kodera, Yoichi

Hosomi, Tatsuhide

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Article abstract of DOI:10.1016/S0040-4039(00)82237-6

A novel oxidative ring-opening reaction of isoxazolidines upon treatment with an electrophile and subsequently with a base gives β-amino ketones and β-amino acid esters highly efficiently.

Full text of DOI:10.1016/S0040-4039(00)82237-6

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