
Tetrahedron p. 4339 - 4350 (1988)
Update date:2022-08-03
Topics: Enantiomer Efficient Synthesis Experimental terms Sesquiterpene
Kitahara, Takeshi
Kurata, Hitoshi
Mori, Kenji
An efficient total synthesis of (+)-sporogen-AO 1 (13-desoxyphomenone) 1 was achieved in 20 steps from ethyl (1R,2S)-5,5-ethylenedioxy-2-hydroxycyclohexanecarboxylate 3 in 8.3percent overall yield.The optically active 3 with 98.4percent e.e. was easily ob
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