PALLADIUM-CATALYZED 1,4-DISILYLATION OF α,β UNSATURATED KETONES WITH 1,1-DICHLORO-1-PHENYL-2,2,2-TRIMETHYLDISILANE

Article abstract of DOI:10.1016/S0040-4039(00)80440-2

1,4-Disilylation of α,β-unsaturated ketones proceeded with 1,1-dichloro-1-phenyl-2,2,2-trimethyldisilane in the presence of a phosphine-palladium catalyst in benzene.Treatment of the disilylation products with an excess of methyllithium generated β-silyl lithium enolates, of which hydrolysis and alkylation gave β-(phenyldimethylsilyl) ketones and anti β-silyl α-alkyl ketones, respectively.