Preparation and reactions of 3-phosphinyl-1-aza-1,3-butadienes. Synthesis of phosphorylated pyridine and pyrazole derivatives

Article abstract of DOI:10.1016/j.tet.2005.11.003

3-Phosphinyl 1-aza-1,3-butadienes 2 are obtained by aldol condensation between hydrazonoalkyl phosphine oxides and N,N-dimethylformamide dimethyl acetal. Transamination reaction of these azadienes with amines yields functionalized 1-aza-1,3-butadienes 3.