ASYMMETRIC SYNTHESIS OF α-AMINO ACIDS: COMPARISON OF ENOLATE VS. CATION FUNCTIONALIZATION OF N-BOC-5,6-DIPHENYL-2,3,5,6-TETRAHYDRO-4H-1,4-OXAZIN-2-ONES

DOI: 10.1016/S0040-4039(00)82268-6

Source and publish data:

Tetrahedron Letters p. 6075 - 6078 (1988)

Update date:2022-09-26

Topics:

Authors:

Williams, Robert M.

Im, Myeong-Nyeo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)82268-6

Enolate generation and subsequent alkylation of the chiral glycinates 1 and 2 occurs with a high degree of diastereoselectivity.Reduction of the homologation products (3 and 4) furnishes with high enantiomeric excess, the N-t-BOC, and free α-amino acid derivates 5 and 6, respectively.

Full text of DOI:10.1016/S0040-4039(00)82268-6

Products guided by the article

Product name:(3R,5R,6S)-3-Allyl-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester

Cas No:123098-59-9

R&D Labs maybe for 123098-59-9

Nantong Auxin Electronic Technology Co., LTD

Contact:86-513-88760026

Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
TIANJIN NORTH JINHENG CHEMICAL PLANT.

Contact:0086-22-59952083

Address:DongShigu Country In JiXian TianJin China
Jinan Boss Chemical Industry Co., Ltd.【revoke the business license】

website:http://www.chemboss.com.cn

Contact:+86-531-58591595

Address:No2.Hualong Road, Jinan, China
EGBERT CORPORATION

Contact:+86 18616952870

Address:Area
JiYi Chemical (Beijing) Co., Ltd.

Contact:+86-10-89385733

Address:Shilou Town of Fangshan District， Beijing

Relevant to this article

Novel synthesis of piperidinecarboxamides via aryl isocyanate acylation of α-amino carbanions

Doi:10.1021/jo00284a048
(1989)
[Bu₄P]⁺Cl^--catalyzed reactions of trichlorosilane and dichloromethylsilane with vinyltrichlorosilane: New synthetic method for 1,1,4,4-tetrachloro-2,5-bis(trichlorosilyl)-1, 4-disilacyclohexane compounds

Doi:10.1021/om100039b
(2010)
The synthesis of GV143253A: A case study for the use of analytical and statistical tools to elucidate the reaction mechanism and to Optimize the process

Doi:10.1021/op100097c
(2010)
Regioselective 1,4-Functionalization of 1,3-Dienes via (η³-1-Acetonylallylic)Fe(CO)2NO Complexes

Doi:10.1246/cl.1999.615
(1989)
Effect of halogen atom localization on the level of antimycobacterial activity of 2-amino-4-arylamino-6-methylpyrimidines

Doi:10.1134/S1070363210040237
(2010)
Solvent Dependence of the Carbon Kinetic Isotope Effect on the Decarboxylation of 4-Pyridylacetic Acid. A model for Enzymatic Decarboxylations

Doi:10.1021/ja00276a031
(1986)

Article Doi