
Chemistry Letters p. 445 - 448 (1989)
Update date:2022-09-26
Topics:
Shirai, Fumiyuki
Nakai, Takeshi
A new synthetic route to the 1β-methylcarbapenem precursor from (S)-methyl 3-hydroxy-2-methylpropanoate has been developed which involves as a key step the chelation-controlled aldol reaction of (S)-3-benzyloxy-2-methylpropanal with ketene trimethylsilyl acetal of ethyl (trimethylsilyl)acetate.
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Doi:10.1016/S0040-4039(01)80270-7
(1989)Doi:10.1021/om00114a026
(1989)Doi:10.1021/ja00202a042
(1989)Doi:10.1016/j.bioorg.2021.105027
(2021)Doi:10.1055/s-0030-1258519
(2010)Doi:10.1021/op100226k
(2010)