Preparation and NMR characterization of hydrogen bonding in 2- and 2,6-bis-(N,N-diethylaminomethyl)-4R-phenols

Article abstract of DOI:10.1016/0022-2860(91)80014-U

A series of Mannich mono- and di-bases derived from 4-substituted phenols were prepared and investigated by 1H and 13C NMR spectroscopy in chloroform-d1 solution.The chemical shifts of intramolecular hydrogen-bonded protons in Mannich bases depend on the