Journal of Medicinal Chemistry p. 371 - 374 (1990)
Update date:2022-07-31
Topics:
Kempf
De Lara
Stein
Cohen
Egan
Plattner
The synthesis of a series of renin inhibitors in which the P2 and P3 amino acids are replaced with the hydroxyethylene dipeptide isostere is reported. In vitro evaluation of the inhibitors has revealed that this isostere is an accept
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