DIAZOCYCLOHEXADIENONES AS PHOTOAFFINITY LIGANDS: SYNTHESES OF TRIOXABICYCLOOCTANE PROBES FOR THE CONVULSANT BINDING SITE OF THE GABAA RECEPTOR

DOI: 10.1016/S0040-4039(01)80625-0

Source and publish data:

Tetrahedron Letters p. 823 - 826 (1989)

Update date:2022-07-29

Topics: Syntheses Binding site

Authors:

Goeldner, Maurice P.

Hawkinson, Jon E.

Casida, John E.

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Article abstract of DOI:10.1016/S0040-4039(01)80625-0

Photoaffinity ligand combines the bromodiazocyclohexadienonyl and t-butyltrioxabicyclo<2,2,2>octane moieties to achieve suitable photochemical properties and affinity for the convulsant binding site of the GABAA receptor.

Full text of DOI:10.1016/S0040-4039(01)80625-0

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