A New Synthesis of 3,4-Diaryl-5-oxo-4,5-dihydroisoxazoles and Their Transformation to 5-isoxazoles and 5-(2-Aminoethylthio)isoxazoles

DOI: 10.1055/s-1989-27221

Source and publish data:

Synthesis p. 275 - 280 (1989)

Update date:2022-08-05

Topics:

Authors:

Dannhardt, Gerd

Laufer, Stefan

Obergrusberger, Irmengard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1989-27221

A novel method to synthesize 3,4-diaryl-5-oxo-4,5-dihydroisoxazoles by addition of methyl lithio(phenyl)acetates to benzonitrile oxides is described.The isoxazolinones are transformed to 5-isoxazoles and 5-(2-aminoethylthio)isoxazol

Full text of DOI:10.1055/s-1989-27221

Products guided by the article

Product name:Isoxazole, 5-chloro-3-(4-chlorophenyl)-4-phenyl-

Cas No:123476-78-8

R&D Labs maybe for 123476-78-8

zhengzhou Triz Pharma-Tech Co., Ltd

website:http://www.Trizpharma-tech.com

Contact:+86-0371-86597269，53392065

Address:High-tech Industrial Development Zone, Zhengzhou City, NO.7 Holly Street
Nanjing Vincero International Trading Co.,Ltd

Contact:8618936897229

Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
Ji'nan Orgachem Pharmaceutical Co.,Ltd

Contact:+86-531-82687810

Address:Jinan
Chengdu Gelipu Biotechnology Co., Ltd.

website:http://www.glp-china.com

Contact:86-28-82610909

Address:chegndu
Ceresking Ecology & Technology co.,ltd

Contact:86 22 66218397

Address:Room 1613, Zheshang Mansion, No. 1988, Yingbin Avenue, Binhai New District, Tianjin,China.

Relevant to this article

Regioselectivity of the protonation of captodative enamines bearing a CF₃ group

Doi:10.1016/j.jfluchem.2009.10.001
(2010)
Nickel(II) and iron(II) complexes with 1-(2(4)-chlorophenyl) benzothiazolylformazans

Doi:10.1134/S1070328410030085
(2010)
1,6-addition of organocopper reagents to 3-alkynyl-2-cycloalkenones: Regiospecific syntheses of dienones and allenes

Doi:10.1021/jo00290a030
(1990)
Synthesis of 10-Alkyl-9-allenylanthracenes involving <3,4>Sigmatropic Rearrangement

Doi:10.1039/c39890000654
(1989)
Studies on the asymmetric, phosphine-promoted [3+2] annulations of allenic esters with 2-aryl-1,1-dicyanoalkenes

Doi:10.1016/j.tetasy.2010.04.014
(2010)
Design, synthesis, and structure-activity relationships of novel bicyclic azole-amines as negative allosteric modulators of metabotropic glutamate receptor 5

Doi:10.1021/jm100736h
(2010)

Article Doi