SYNTHESIS OF 2'- AND 3'-AZIDO-2',3'-DIDEOXYADENOSINES. PREPARATIVE APPLICATIONS OF THE DEOXYGENATIVE-HYDRIDE SHIFT AND β-ELIMINATION REACTIONS OF O-SULFONYLATED ADENOSINES

Article abstract of DOI:10.1016/0008-6215(89)84088-1

2'-Azido-2',3'-dideoxyadenosine (9) has been synthesized from adenosine (1) in 6-8 steps.The key intermediate, N⁶,O⁵'-bis(4,4'-dimethoxytrityl)-9-(3-deoxy-β-D-threo-pentofuranosyl)adenine (6a), was prepared in a one-flask manner by t