Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure-activity relationships of novel dicamphanoyl-2′,2′- dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents

DOI: 10.1016/j.bmc.2010.07.065

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Bioorganic and Medicinal Chemistry p. 6678 - 6689 (2010)

Update date:2022-09-26

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Authors:

Zhou, Ting

Shi, Qian

Chen, Chin-Ho

Zhu, Hao

Huang, Li

Ho, Phong

Lee, Kuo-Hsiung

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Article abstract of DOI:10.1016/j.bmc.2010.07.065

In a continued study, 23 3′R,4′R-di-O-(-)-camphanoyl-2′, 2′-dimethyldihydropyrano[2,3-f]chromone (DCP) derivatives (5-27) were synthesized, and screened for anti-HIV activity against both a non-drug-resistant NL4-3 strain and multiple reverse transcriptas

Full text of DOI:10.1016/j.bmc.2010.07.065

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