Tetrahedron Letters p. 3307 - 3308 (1989)
Update date:2022-09-26
Topics:
Hong, Seongkuk
Chang, Kyeongho
Ku, Bonchul
Oh, Dong Young
A new synthetic route to β-keto phosphonates from diethyl 1-(trimethylsilyl)vinylphosphonate 1 is described.This involves nucleophilic addition of the organolithium reagents toward 1 followed by quenching with acid chlorides and alkyl isocyanates.
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