Structure-activity relationship study of glaziovianin A against cell cycle progression and spindle formation of HeLa S3 cells

DOI: 10.1016/j.bmcl.2010.07.111

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Bioorganic and Medicinal Chemistry Letters p. 5402 - 5404 (2010)

Update date:2022-07-29

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Authors:

Ikedo, Akiyuki

Hayakawa, Ichiro

Usui, Takeo

Kazami, Sayaka

Osada, Hiroyuki

Kigoshi, Hideo

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Article abstract of DOI:10.1016/j.bmcl.2010.07.111

Various derivatives of glaziovianin A, an antitumor isoflavone, were synthesized, and the cytotoxicity of each against HeLa S₃ cells was investigated. Compared to glaziovianin A, the O⁷-allyl derivative was found to be more cytotoxic

Full text of DOI:10.1016/j.bmcl.2010.07.111

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