Central cholinergic agents. III. Synthesis of 2-alkoxy-2,8-diazaspiro[4.5]decane-1,3-diones as muscarinic agonists

DOI: 10.1248/cpb.40.1177

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1177 - 1185 (1992)

Update date:2022-08-04

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Authors:

Ishihara

Yukimasa

Miyamoto

Goto Goto

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Article abstract of DOI:10.1248/cpb.40.1177

A series of 2-alkoxy-2,8-diazaspiro[4.5]decane-1,3-diones and related compounds were synthesized and tested for muscarinic receptor binding affinity using [³H]pirenzepine and [³H]oxotremorine M as ligands. They were also evaluated fo

Full text of DOI:10.1248/cpb.40.1177

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Product name:1,4,8-Triazaspiro[4.5]decane-1-carboxylic acid, 2,8-dimethyl-3-oxo-, phenylmethyl ester

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