Synthesis and tumor cytotoxicity of novel amide derivatives of β-hederin

DOI: 10.3390/molecules15117871

Source and publish data:

Molecules p. 7871 - 7883 (2010)

Update date:2022-07-29

Topics:

Authors:

Liu, Yang

Lu, Wen-Xiang

Yan, Mao-Cai

Yu, Yang

Ikejima, Takashi

Cheng, Mao-Sheng

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Article abstract of DOI:10.3390/molecules15117871

Thirteen novel triterpenoid saponins, designed as amide derivatives of the natural cytotoxic saponin α-hederin, were synthesized by a stepwise glycosylation strategy. The in vitro cytotoxic activity of these compounds was evaluated against five different

Full text of DOI:10.3390/molecules15117871

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