SYNTHESIS AND CARBAMOYLATION OF 1,2,3,4,5,6-HEXAHYDRO-1,3-DIMETHYL-2,6-METHANO-1,3-BENZODIAZOCIN-8-OL: BRIDGED ANALOGUES OF PHYSOSTIGMIN

DOI: 10.1016/0040-4039(92)88151-T

Source and publish data:

Tetrahedron Letters p. 2103 - 2106 (1992)

Update date:2022-08-05

Topics:

Authors:

Fink, David M.

Allen, Richard C.

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Article abstract of DOI:10.1016/0040-4039(92)88151-T

The synthesis and carbamoylation of 2,6-methano-1,3-benzodiazocin-8-ol is described.A one pot silyl-aryl ether to carbamate transformation was developed.The compounds are analogues of the cholinesterase inhibitor physostigmin.

Full text of DOI:10.1016/0040-4039(92)88151-T

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