SYNTHESIS AND CARBAMOYLATION OF 1,2,3,4,5,6-HEXAHYDRO-1,3-DIMETHYL-2,6-METHANO-1,3-BENZODIAZOCIN-8-OL: BRIDGED ANALOGUES OF PHYSOSTIGMIN

DOI: 10.1016/0040-4039(92)88151-T

Source and publish data:

Tetrahedron Letters p. 2103 - 2106 (1992)

Update date:2022-08-05

Topics:

Authors:

Fink, David M.

Allen, Richard C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(92)88151-T

The synthesis and carbamoylation of 2,6-methano-1,3-benzodiazocin-8-ol is described.A one pot silyl-aryl ether to carbamate transformation was developed.The compounds are analogues of the cholinesterase inhibitor physostigmin.

Full text of DOI:10.1016/0040-4039(92)88151-T

Products guided by the article

Product name:6-Methoxy-4-methoxycarbonylmethyl-2-oxo-1,2,3,4-tetrahydro-quinoline-3-carboxylic acid methyl ester

Cas No:125810-74-4

R&D Labs maybe for 125810-74-4

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

website:http://www.shydtec.com

Contact:86-21-57721279

Address:Science and Technology Park, Songjiang District, Shanghai, China
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Huangshi Meifeng Chemical Co.,ltd.

Contact:+86-714-6516706

Address:1941-4-3#,Hubin Avenue,Huangshi,Hubei,China
Nanjing HuiBaiShi Biotechnology Co.,Ltd.

Contact:+86 (25)58745219

Address:No.606 Ningliu Road,LiuHe District.
suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China

Relevant to this article

Navigating CYP1A Induction and Arylhydrocarbon Receptor Agonism in Drug Discovery. A Case History with S1P₁ Agonists

Doi:10.1021/acs.jmedchem.5b01102
(2015)
P-(benzyloxy)calix[8]arene synthesis revisited: P-(benzyloxy)calix[4]-, p-(benzyloxy)calix[5]-, p-(benzyloxy)calix[7]-, and p-(benzyloxy)bis(homooxa) calix[4]arenes

Doi:10.1002/ejoc.200901405
(2010)
Synthesis, structure, and reductive elimination in the series Tp′Rh(PR₃)(Ar^F)H; Determination of rhodium-carbon bond energies of fluoroaryl substituents

Doi:10.1039/c0dt00157k
(2010)
Gold versus palladium: A regioselective cycloisomerization of aromatic enynes

Doi:10.1002/adsc.201300746
(2013)
Reactive thermoresponsive copolymer scaffolds

Doi:10.1039/c0cc03856c
(2010)
5-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-2(1H)-quinolinones and 3,4-dihydro-2(1H)-quinolinones: Dual-acting 5-HT₁ receptor antagonists and serotonin reuptake inhibitors. Part 3

Doi:10.1016/j.bmcl.2010.09.085
(2010)

Article Doi