On pyrrolidine derivatives I. An efficient synthesis of 3-substituted (2S,5S)-pyrrolidine-2,5-dicarboxylic acids

DOI: 10.1002/jhet.5570260322

Source and publish data:

Journal of Heterocyclic Chemistry p. 629 - 634 (1989)

Update date:2022-08-03

Topics: Synthesis Derivatives Pyrrolidine Substituted Efficient Synthesis Experimental

Authors:

Honma Honma

Tada Tada

Adachi Adachi

Igarashi

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Article abstract of DOI:10.1002/jhet.5570260322

(2S,5S)-3-Alkylpyrrolidine-2,5-dicarboxylic acid derivatives I were stereoselectively synthesized by means of an efficient method starting from L-aspartic acid. (1) Dieckmann reaction of 4-benzyl l-t-butyl N-t-butyl-oxycarbonyl-N-ethoxycarbonylmethyl-L-as

Full text of DOI:10.1002/jhet.5570260322

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