4-(((4-Iodophenyl)methyl)-4H-1,2,4-triazol-4-ylamino)-benzonitrile: A Potential Imaging Agent for Aromatase

DOI: 10.1021/acs.jmedchem.6b00849

Source and publish data:

Journal of Medicinal Chemistry p. 9370 - 9380 (2016)

Update date:2022-08-03

Topics:

Authors:

Song, Jin

Wu, Zehui

Wangtrakuldee, Beau

Choi, Seok Rye

Zha, Zhihao

Ploessl, Karl

Mach, Robert H.

Kung, Hank

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Article abstract of DOI:10.1021/acs.jmedchem.6b00849

Aromatase (CYP19) is a rate-limiting enzyme that catalyzes the biosynthesis of estrogens. Imaging agents based on aromatase inhibitors (AIs) have been developed for a PET/SPECT study. A series of compounds was synthesized based on YM511, which has previou

Full text of DOI:10.1021/acs.jmedchem.6b00849

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Product name:4-((4H-1,2,4-triazol-4-yl)(4-(tributylstannyl)benzyl)amino)benzonitrile

Cas No:1260369-03-6

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