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Antitumor agents. V. Synthesis and antileukemic activity of E-ring-modified (RS)-camptothecin analogues

DOI: 10.1248/cpb.40.683

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 683 - 688 (1992)

Update date:2022-07-31

Topics:

Authors:

EjimaEjima

TerasawaTerasawa

SugimoriSugimori

OhsukiOhsuki

MatsumotoMatsumoto

KawatoKawato

YasuokaYasuoka

TagawaTagawa

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Article abstract of DOI:10.1248/cpb.40.683

Several E-ring-modified analogues of (RS)-camptothecin were synthesized by total synthesis via Friedlander condensation and evaluated for cytotoxicity and antitumor activity against P388 mouse leukemia cells. Among them, (RS)-20-deoxyamino-7-ethyl-10-meth

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Full text of DOI:10.1248/cpb.40.683

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Products guided by the article

Product name:7-ethyl-10-hydroxy-20-deoxyaminocamptothecin

Cas No:126266-01-1

126266-01-1

R&D Labs maybe for 126266-01-1

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