Antitumor agents. V. Synthesis and antileukemic activity of E-ring-modified (RS)-camptothecin analogues

DOI: 10.1248/cpb.40.683

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 683 - 688 (1992)

Update date:2022-07-31

Topics:

Authors:

Ejima Ejima

Terasawa

Sugimori

Ohsuki Ohsuki

Matsumoto

Kawato Kawato

Yasuoka Yasuoka

Tagawa Tagawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.683

Several E-ring-modified analogues of (RS)-camptothecin were synthesized by total synthesis via Friedlander condensation and evaluated for cytotoxicity and antitumor activity against P388 mouse leukemia cells. Among them, (RS)-20-deoxyamino-7-ethyl-10-meth

Full text of DOI:10.1248/cpb.40.683

NII-Electronic Library Service

Products guided by the article

Product name:7-ethyl-10-hydroxy-20-deoxyaminocamptothecin

Cas No:126266-01-1

R&D Labs maybe for 126266-01-1

Huaihua Baohua Biotechnology Co.,Ltd

website:http://www.baochengchem.com

Contact:86-519-82698291

Address:HouYang chemical development zone,Jintan,Jiangsu,China (213200)
Hangzhou J&H Chemical Co., Ltd.

website:http://www.jhechem.com/

Contact:+86-571-87396432

Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China
CHEMINN LTD.

website:http://www.cheminn.com/

Contact:86-531-67875205

Address:No.9-2,South of Shanda Road, Jinan ,China
Xinji City Taida Sinopec Co., Ltd.

Contact:0086-311-85341278

Address:No.6, Nanhua Road,Xinji City Road,Hebei Province,China
Nanjing Zelang Medical Technology Co. Ltd

Contact:86-25-83063290/13770714480

Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China

Relevant to this article

Nano copper(II) oxide catalyzed four-component synthesis of functionalized benzo[a]pyrano[2,3-c]phenazine derivatives

Doi:10.1016/j.crci.2012.09.012
(2012)
Gold-catalyzed diastereoselective synthesis of α-fluoroenones from propargyl acetates

Doi:10.1055/s-0030-1258992
(2010)
3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors. 7. Modification of the Hexahydronaphthalene Moiety of Simvastanin: 5-Oxygenated and 5-Oxa Derivatives

Doi:10.1021/jm00112a027
(1991)
Synthesis and spectrophotometric study of acidic and complexing properties of 5,15-bis(4'-methoxyphenyl)-10,20-bis(4″-nitrophenyl)-2,8,12,18-tetramethyl-3,7,13,17-tetraethylporphyn in acetonitrile

Doi:10.1134/S1070363215030196
(2015)
A versatile synthesis of 3-substituted 4-cyano-1,2,3,4-tetrahydro-1-oxo- β-carbolines

Doi:10.1055/s-0030-1258282
(2010)
Synthesis of 3-substituted derivatives of 2,2,6,6-tetramethylpiperidine- N-alkoxyamine ethers: Novel alkoxyamine building blocks

Doi:10.1055/s-0030-1258255
(2010)

Article Doi