BROMOALKYLPHTALAZINONES AND ISOMERIC OXAZOLINIUM SALTS AS INTERMEDIATES AND SYNTHONS

Article abstract of DOI:10.1016/S0040-4020(01)89500-4

2(ο-Piperidinoalkyl)phtalazin-1(2H)-ones can be prepared from the 2-hydroxyalkyl compounds both via the open-chain 2-bromoalkyl derivatives and via their cyclic isomers.Substitution reactions of bromoalkyl compounds may be assisted by polar solvents and b