Carboxypeptidase A Catalyzed α,β-Elimination Reactions: Rapid Catalysis of α,β-Elimination of Hydrogen Chloride from β-Chloro Ketone Substrates

DOI: 10.1021/ja00270a033

Source and publish data:

Journal of the American Chemical Society p. 2710 - 2715 (1986)

Update date:2022-08-03

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Authors:

Nashed, Nashaat T.

Kaiser, E. T.

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Article abstract of DOI:10.1021/ja00270a033

The proteolytic enzyme carboxypeptidase A (CPA) catalyzes α,β-elimination of hydrogen chloride from 2-benzyl-2-chloro-3-(4-methoxybenzoyl)propionic acid (I), 2-benzyl-2-chloro-3-benzoylpropionic acid (II), and 2-chloro-2-methyl-3-benzoylpropionic acid (II

Full text of DOI:10.1021/ja00270a033

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