Cardiotonic agents. 6. Histamine analogues as potential cardiovascular selective H2 agonists

DOI: 10.1021/jm00168a024

Source and publish data:

Journal of Medicinal Chemistry p. 1688 - 1697 (1990)

Update date:2022-08-04

Topics:

Authors:

Lampe Lampe

Hanna Hanna

Piscitelli

Chou Chou

Erhardt Erhardt

Lumma Jr.

Greenberg

Ingebretsen

Marshall

Wiggins Wiggins

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Article abstract of DOI:10.1021/jm00168a024

Twenty-six alkyl and aralkyl histamine analogues were prepared as potential cardiotonic agents. Compounds were designed to allow interaction with a putative secondary aryl binding site at the H₂ receptor, the presence of which was inferred from

Full text of DOI:10.1021/jm00168a024

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