
Tetrahedron Letters p. 3655 - 3656 (1989)
Update date:2022-08-02
Topics: Aldehydes Conversion Terminal alkynes Experimental procedure Homologation
Hijfte, Luc Van
Kolb, Michael
Witz, Pascale
A convenient method for the conversion of aldehydes to terminal alkynes via the corresponding 1,1-dibromoalkenes is described.The key feature of the process is the use of megnesium in tetrahydrofuran for the debromination step.
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Doi:10.1142/S1088424610002744
(2010)Doi:10.1021/ol103149b
(2011)Doi:10.1002/ejoc.201001021
(2011)Doi:10.1007/BF00962159
(1989)Doi:10.1007/BF00764437
(1989)Doi:10.2298/JSC100104004A
(2011)