A PRACTICAL PROCEDURE FOR THE CONVERSION OF ALDEHYDES TO TERMINAL ALKYNES BY A ONE CARBON HOMOLOGATION

DOI: 10.1016/S0040-4039(01)80473-1

Source and publish data:

Tetrahedron Letters p. 3655 - 3656 (1989)

Update date:2022-08-02

Topics: Aldehydes Conversion Terminal alkynes Experimental procedure Homologation

Authors:

Hijfte, Luc Van

Kolb, Michael

Witz, Pascale

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Article abstract of DOI:10.1016/S0040-4039(01)80473-1

A convenient method for the conversion of aldehydes to terminal alkynes via the corresponding 1,1-dibromoalkenes is described.The key feature of the process is the use of megnesium in tetrahydrofuran for the debromination step.

Full text of DOI:10.1016/S0040-4039(01)80473-1

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