A NEW, SHORT SYNTHETIC ROUTE TO α-SUBSTITUTED 5,5-DIFLUORO-4-PENTENOIC ACID ESTERS

Article abstract of DOI:10.1016/S0022-1139(00)84151-2

The title compounds are prepared in one step from ester enolates and 3,3,3-trifluoropropene.The α-substituted 5,5-difluoro-4-pentenoic acid esters are susceptible to a second deprotonation and, on reaction with an electrophile, give access to the α-disubs