Synthesis and antinociceptive activity of 9-phenyl-oxy or 9-acyl-oxy derivatives of xanthene, thioxanthene and acridine

Article abstract of DOI:10.1016/0223-5234(89)90083-4

The synthesis of 9-alkyl-oxy or 9-acyl-oxy derivatives of xanthene, thioxanthene and acridine is reported.A potent antinociceptive activity was confirmed for the 9-phenyl-9-propionyl-oxy derivative bearing an oxygen or sulfur atom in the heteroaromatic structure. xanthene derivatives/ thioxanthene derivatives/ acridine derivatives/ trimepridine analogues/ antinociceptive activity