Tetrahedron Letters p. 4645 - 4648 (1989)
Update date:2022-07-29
Topics:
Bernatowicz, Michael S.
Daniels, Scott B.
Koester, Hubert
Substituted benzhydrylamine and benzylamine linkage agents useful for the solid phase peptide synthesis of C-terminal amides were evaluated for their relative lability toward trifluoroacetic acid.The two most reactive linkage agents studied were compared in the synthesis of two different peptide amides by the N α-9-fluorenylmethyloxycarbonyl protecting group strategy.
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