Regioselective Alkylation of 4,6-Bis(methylthio)-1H-pyrazolopyrimidine

DOI: 10.1055/s-1989-27421

Source and publish data:

Synthesis p. 876 - 878 (1989)

Update date:2022-08-03

Topics:

Authors:

Garg, Neeraj

Avasthi, K.

Bhakuni, D. S.

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Article abstract of DOI:10.1055/s-1989-27421

Reaction of 4,6-bis(methylthio)-1H-pyrazolo<3,4-d>pyrimidine with alkyl halides in the presence of sodium hydride produces predominantly 2-alkyl-4,6-bis(methylthio-2H-pyrazolo<3,4-d>pyrimidines in good yields.

Full text of DOI:10.1055/s-1989-27421

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Product name:4,6-Bis(methylthio)-2-propyl-2H-pyrazolo<3,4-d>pyrimidine

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