Simple analogs of acromelic acid, which are highly active agonists of kainate type neuroexcitant

DOI: 10.1016/S0040-4039(00)97239-3

Source and publish data:

Tetrahedron Letters p. 7047 - 7050 (1990)

Update date:2022-08-05

Topics:

Authors:

Hashimoto, Kimiko

Horikawa, Manabu

Shirahama, Haruhisa

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Article abstract of DOI:10.1016/S0040-4039(00)97239-3

The highly stereoselective synthesis of acromelic acid analogs; 3a and 3b, was achieved. The new kainoid 3b was found to be the strongest neuroexcitant among the kainoids known so far.

Full text of DOI:10.1016/S0040-4039(00)97239-3

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