
Tetrahedron Letters p. 6081 - 6084 (1989)
Update date:2022-09-26
Topics:
Carling
Curtis
Holmes
Methylenation of the racemic lactone, followed by stereoselective hydroboration, gave predominantly the trans-2,9-disubstituted oxonane which was converted into the carbon skeleton of obtusenyne. Epimerisation of the trans-aldehyde gave the cis-compound.
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