Efficient Preparation of Intermediates Corresponding to C22-C27 and C28-C34 of FK-506

DOI: 10.1021/jo00296a040

Source and publish data:

Journal of Organic Chemistry p. 2771 - 2776 (1990)

Update date:2022-07-31

Topics:

Authors:

Linde, II Robert G.

Egbertson, Melissa

Coleman, Robert S.

Jones, A. Brian

Danishefsky, Samuel J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00296a040

Efficient large-scale preparations of aldehyde 2 and sulfone 3 representing the C22-C27 and C28-C34 potions of the immunosuppressant FK-506 (1) are descibed.

Full text of DOI:10.1021/jo00296a040

Products guided by the article

Product name:methyl 2,4-di-O-(4-methoxybenzylidene)-3-deoxy-3-methyl-α-D-idopyranoside

Cas No:127258-11-1

R&D Labs maybe for 127258-11-1

Aminodiscovery Co.,Ltd.

Contact:+86-535-8888888

Address:No.161 Haishi Rd.
Zibo Xiaoguang Chemical Material Co., Ltd

Contact:15954099116

Address:Boshan Development Zone
Winchem Industrial Co. Ltd.(expird)

Contact:86-574-83851061 86-574-87083208

Address:Room 905, No.3 Building,East Business Center, 456 Xingning Road, Ningbo City,China
Shenzhen ZheYi Chemicals Co.,LTD(Shanghai Branch)

Contact:+86-21-54159691

Address:Room1002,Building No.2, Lane 98 Bixiu Road,Minhang District, Shanghai,China 201100
Hongyi Import & Export CO.,LTD

Contact:86-13319649499

Address:Nanzheng Neighborhood Commitees, Chongwen Office, Yongding District

Relevant to this article

Synthesis of Dihydro-1H-indenes via a Formal 3 + 2 Cycloaddition of p-Quinone Methides and Styrenes

Doi:10.1021/jo00299a003
(1990)
One-pot activation-alkynylation-cyclization synthesis of 1,5-diacyl-5-hydroxypyrazolines in a consecutive three-component fashion

Doi:10.3762/bjoc.15.136
(2019)
Protecting group free synthesis of 6-substituted naphthols and binols

Doi:10.1021/jo1025892
(2011)
Well-defined N-heterocyclic carbene silver halides of 1-cyclohexyl-3- arylmethylimidazolylidenes: Synthesis, structure and catalysis in A ³-reaction of aldehydes, amines and alkynes

Doi:10.1039/c0dt01074j
(2011)
Synthesis and Antiviral Activity of (S)-9-<4-Hydroxy-3-(phosphonomethoxy)butyl>guanine

Doi:10.1021/jm00168a039
(1990)
β-diketiminate stabilized magnesium hydroxide, heterobimetallic, and halide complexes: Synthesis and X-ray structural studies

Doi:10.1002/zaac.201000348
(2011)

Article Doi