Efficient Preparation of Intermediates Corresponding to C22-C27 and C28-C34 of FK-506

DOI: 10.1021/jo00296a040

Source and publish data:

Journal of Organic Chemistry p. 2771 - 2776 (1990)

Update date:2022-07-31

Topics:

Authors:

Linde, II Robert G.

Egbertson, Melissa

Coleman, Robert S.

Jones, A. Brian

Danishefsky, Samuel J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00296a040

Efficient large-scale preparations of aldehyde 2 and sulfone 3 representing the C22-C27 and C28-C34 potions of the immunosuppressant FK-506 (1) are descibed.

Full text of DOI:10.1021/jo00296a040

Products guided by the article

Product name:methyl 2,4-di-O-(4-methoxybenzylidene)-3-deoxy-3-methyl-α-D-idopyranoside

Cas No:127258-11-1

R&D Labs maybe for 127258-11-1

CHENGDU CHENLV HERB CO.,LTD

Contact:+86-28-88523492

Address:714rooms of Time Square, Pujiang County
Jining Shengrun Chemical Industry Co., Ltd.

Contact:+86-537-7121666 ,

Address:West Ring Road,Wenshang County Shandong Province
HuiFeiChem PharmaTech Co.Ltd

Contact:0510-85393305

Address:1619 Huishan Avenue, Huishan District, Wuxi,
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-5161 3915

Address:Shanghai YangPu
Luoyang Aoda chemical Co.,Ltd.

Contact:+86-379-67518785 67516588

Address:MiaoWan industry district,YanShi City,Henan,China

Relevant to this article

Synthesis of Dihydro-1H-indenes via a Formal 3 + 2 Cycloaddition of p-Quinone Methides and Styrenes

Doi:10.1021/jo00299a003
(1990)
One-pot activation-alkynylation-cyclization synthesis of 1,5-diacyl-5-hydroxypyrazolines in a consecutive three-component fashion

Doi:10.3762/bjoc.15.136
(2019)
Protecting group free synthesis of 6-substituted naphthols and binols

Doi:10.1021/jo1025892
(2011)
Well-defined N-heterocyclic carbene silver halides of 1-cyclohexyl-3- arylmethylimidazolylidenes: Synthesis, structure and catalysis in A ³-reaction of aldehydes, amines and alkynes

Doi:10.1039/c0dt01074j
(2011)
Synthesis and Antiviral Activity of (S)-9-<4-Hydroxy-3-(phosphonomethoxy)butyl>guanine

Doi:10.1021/jm00168a039
(1990)
β-diketiminate stabilized magnesium hydroxide, heterobimetallic, and halide complexes: Synthesis and X-ray structural studies

Doi:10.1002/zaac.201000348
(2011)

Article Doi