Efficient Preparation of Intermediates Corresponding to C22-C27 and C28-C34 of FK-506

DOI: 10.1021/jo00296a040

Source and publish data:

Journal of Organic Chemistry p. 2771 - 2776 (1990)

Update date:2022-07-31

Topics:

Authors:

Linde, II Robert G.

Egbertson, Melissa

Coleman, Robert S.

Jones, A. Brian

Danishefsky, Samuel J.

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Article abstract of DOI:10.1021/jo00296a040

Efficient large-scale preparations of aldehyde 2 and sulfone 3 representing the C22-C27 and C28-C34 potions of the immunosuppressant FK-506 (1) are descibed.

Full text of DOI:10.1021/jo00296a040

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